DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme.
نویسندگان
چکیده
We show that nucleotides which are modified with a G-quadruplex-derived DNAzyme are substrates for DNA polymerases. Based on this finding we developed a naked-eye detection system that allows the detection of single nucleotide variations in DNA.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 34 شماره
صفحات -
تاریخ انتشار 2015